Histamine and Cold Adaptation
- 1 January 1963
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 112 (1) , 25-26
- https://doi.org/10.3181/00379727-112-27939
Abstract
Rats exposed to cold (6°C) for one month show a very rapid and sustained increase in urinary histamine. At the end of this period animals develop a certain tolerance to histamine aerosols. This modification in histamine excretion in the cold possibly reflects mast cell changes and the decreased sensitivity to this amine in cold adapted animals would indicate levels of secretion above physiological requirements.Keywords
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