Total synthesis of the ravidomycin aglycone (defucogilvocarcin V)
- 1 February 1987
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 65 (2) , 427-431
- https://doi.org/10.1139/v87-072
Abstract
The synthesis of 1-hydroxy-10,12-dimethoxy-8-vinyl-6H-benzo[d]naphtho[1, 2b]pyran-6-one 7, starting from vanillin and 1,5-dihydroxynaphthalene is described. This compound is the aglycone of the antitumor antibiotic ravidomycin and is identical with the recently reported antimicrobial agent, defucogilvocarcin V.This publication has 1 reference indexed in Scilit:
- Antitumor agents from Streptomyces anandii: gilvocarcins V, M and E.The Journal of Antibiotics, 1981