The Effects of Age on Late Components of the ERP and Reaction Time

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Abstract
The effects of age on late component ( N100 , P200 , N200 , and P300 ) event - related potentials ( ERP ) and reaction time ( RT ) were investigated in 50 normal subjects , 18 to 70 years of age . A conventional auditory oddball paradigm was employed . An equal number of subjects , as well as an equal number of males and females , were examined in each decade . There were no significant associations found between ERP amplitude and age . A significant positive correlation was found between age and N200 / P300 latency . There were no significant effects of age on R T in the overall group . However , females had slower RT and decreased P200 and N200 amplitude as compared with males . Moreover , males had sig nificant correlations between N200 latency and R T , whereas females showed significant correlations between P300 amplitude and R T . ERP / R T effects should be further explicated between gender , as well as across age .

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