Stereoselective Synthesis of the LM Ring Moiety of Ciguatoxin: Reagent Control of Asymmetric Dihydroxylation
- 1 September 1997
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 26 (9) , 845-846
- https://doi.org/10.1246/cl.1997.845
Abstract
Stereoselective synthesis of the LM ring moiety of ciguatoxin was achieved from (R)-(E)-1-benzyloxy-2-hydroxy-3-pentene via Ireland-Claisen rearrangement, iodolactonization, and reagent-controlled asymmetric dihydroxylation.Keywords
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