Combined Screening With Ultrasound and Mammography vs Mammography Alone in Women at Elevated Risk of Breast Cancer
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Open Access
- 14 May 2008
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 299 (18) , 2151-2163
- https://doi.org/10.1001/jama.299.18.2151
Abstract
Early detection reduces deaths due to breast cancer. The US Preventive Services Task Force analysis of 7 randomized trials of mammographic screening found that the point estimate of the reduction in mortality from screening mammography was 22% in women aged 50 years or older and 15% among women between 40 and 49 years,1 with some individual trials showing far greater benefits in both age groups and with any specific age distinction arbitrary. The magnitude of reduction in mortality seen in individual trials parallels reductions in size distribution2 and rates of node-positive breast cancer.3Keywords
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