The influence of codon context on genetic code translation
- 10 July 1980
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 286 (5769) , 123-127
- https://doi.org/10.1038/286123a0
Abstract
A class of mutations that increase the efficiency of a suppressor tRNA in translating a particular amber codon has been characterized. The increased efficiency is due to a mutation resulting in a change in the mRNA that affects the nucleotide adjacent to the 3′ side of the UAG triplet. Thus the interaction of tRNA with mRNA is influenced by mRNA sequences outside the triplet codon.Keywords
This publication has 43 references indexed in Scilit:
- Identification of transfer RNA suppressors in Escherichia coliJournal of Molecular Biology, 1979
- Site-directed mutations in the initiator region of the bacteriophage Qβ coat cistron and their effect on ribosome bindingJournal of Molecular Biology, 1978
- Biosynthesis of pseudouridine in the in vitro transcribed tRNATyr precursorFEBS Letters, 1977
- Coding properties of an ochre-suppressing derivative of Escherichia coli tRNAITyrJournal of Molecular Biology, 1977
- The influence of the reading context upon the suppression of nonsense codonsMolecular Genetics and Genomics, 1977
- A functional requirement for modification of the wobble nucleotide in the anticodon of a T4 suppressor tRNACell, 1976
- Effect of neighboring nucleotide sequences on suppression efficiency in amber mutants of T4 phage lysozymeMolecular Genetics and Genomics, 1976
- Mutant tRNAHis Ineffective in Repression and Lacking Two Pseudouridine ModificationsNature New Biology, 1972
- Adjacent effect on suppression efficiencyMolecular Genetics and Genomics, 1970
- The influence of the reading context upon the suppression of nonsense codonsMolecular Genetics and Genomics, 1969