Pharmacological Studies on Crude Drugs. VII

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Abstract
Examinations were made on the constituents of crude drugs used frequently as aromatic stomachics, and seven kinds of essential oils including Japanese peppermint oil and fennel oil, for their yield and various properties, qualitative and quantitative determination of their componental constituents by gas chromatography, direct action on excised mouse intestine, antispasmodic action, their action on the rate of transfer of intestinal content. some considerations were then made on the acceleration of gastrointestinal functions and gas elimination, which are considered to be the main pharmacological effect of these crude drugs.Polyethylene glycol 6000 was used as the stationary phase in gas chromatography and a fairly good result was obtained in the analysis of essential oil components. These results were highly similar to the data published to date in literature. These essential oils and their components generally showed antispasmodic action. They did not show any action of accelerating the transfer of intestinal content but rather suppressed such a movement in some cases. The effect of essential oils on human body is more likely to be thought secondary effect via the olfactory and taste senses.

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