Automated detection of exudates for diabetic retinopathy screening
- 5 December 2007
- journal article
- Published by IOP Publishing in Physics in Medicine & Biology
- Vol. 52 (24) , 7385-7396
- https://doi.org/10.1088/0031-9155/52/24/012
Abstract
Automated image analysis is being widely sought to reduce the workload required for grading images resulting from diabetic retinopathy screening programmes. The recognition of exudates in retinal images is an important goal for automated analysis since these are one of the indicators that the disease has progressed to a stage requiring referral to an ophthalmologist. Candidate exudates were detected using a multi-scale morphological process. Based on local properties, the likelihoods of a candidate being a member of classes exudate, drusen or background were determined. This leads to a likelihood of the image containing exudates which can be thresholded to create a binary decision. Compared to a clinical reference standard, images containing exudates were detected with sensitivity 95.0% and specificity 84.6% in a test set of 13,219 images of which 300 contained exudates. Depending on requirements, this method could form part of an automated system to detect images showing either any diabetic retinopathy or referable diabetic retinopathy.Keywords
This publication has 16 references indexed in Scilit:
- Automated Detection and Differentiation of Drusen, Exudates, and Cotton-Wool Spots in Digital Color Fundus Photographs for Diabetic Retinopathy DiagnosisInvestigative Opthalmology & Visual Science, 2007
- Automatic detection of retinal anatomy to assist diabetic retinopathy screeningPhysics in Medicine & Biology, 2006
- Automated microaneurysm detection using local contrast normalization and local vessel detectionIEEE Transactions on Medical Imaging, 2006
- Automated Assessment of Diabetic Retinal Image Quality Based on Clarity and Field DefinitionInvestigative Opthalmology & Visual Science, 2006
- Comparison of Diagnosis of Early Retinal Lesions of Diabetic Retinopathy Between a Computer System and Human ExpertsArchives of Ophthalmology (1950), 2001
- Preservation of sight in diabetes: developing a national risk reduction programmeDiabetic Medicine, 2000
- Automated detection of microaneurysms in digital red‐free photographs: a diabetic retinopathy screening toolDiabetic Medicine, 2000
- Cost effectiveness analysis of screening for sight threatening diabetic eye diseaseBMJ, 2000
- Screening for diabetic retinopathy using computer based image analysis and statistical classificationComputer Methods and Programs in Biomedicine, 2000
- A fully automated comparative microaneurysm digital detection systemEye, 1997