An Efficient Preparation of Macrocycles Bearing Vinamidine Moieties by the Cyclocondensation of Malonaldehyde Derivatives and 1,ω-Diaminoalkanes

Abstract
An efficient preparation of macrocycles 7 and 9 bearing vinamidine moieties is described. The key to the preparation is the (2:2) cyclocondensation of malonaldehyde derivatives 1 and 8 and 1,ω-diaminoalkanes 6.

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