Expression and Localization of Bestrophin during Normal Mouse Development

1 August 2003

journal article
Published by Association for Research in Vision and Ophthalmology (ARVO) in Investigative Opthalmology & Visual Science

Vol. 44 (8) , 3622-3628
https://doi.org/10.1167/iovs.03-0030

Abstract

Purpose. Best macular dystrophy is caused by mutations in the VMD2 gene, which encodes the protein bestrophin. The purpose of this study was to determine the postnatal onset of expression of bestrophin mRNA and protein in the mouse retinal pigment epithelium (RPE).

Keywords

PROTEIN EXPRESSION
POLYMERASE CHAIN REACTION
REAL TIME
IMMUNOHISTOCHEMISTRY
QUANTITATIVE PCR
PROTEINS