Pole-assignment self-tuning control of blood pressure in postoperative patients: a simulation study
- 1 January 1989
- journal article
- Published by Institution of Engineering and Technology (IET) in IEE Proceedings D Control Theory and Applications
- Vol. 136 (1) , 1-11
- https://doi.org/10.1049/ip-d.1989.0001
Abstract
Pole-placement self-tuning control applied to the management of hypertensive patients following surgery is considered via extensive simulation studies on a clinically evaluated model. This model has complexities involving a recirculation term and two threshold-switchable reflex loops due to angiotensin and epinephrine. In this work, further extensions have been made to include drug saturation effects, time-varying patient gains and drug concentration changes. Results are also shown for the self-tuner performance in the presence of coloured noise as obtained from clinical trials. Providing the poleplacement self tuner is jacketed during initial start-up and under sudden transitions, it is shown to perform adequately in simulations of this medical application.Keywords
This publication has 1 reference indexed in Scilit:
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