Nuclease cleavage of chromatin at 100-nucleotide pair intervals
- 1 December 1976
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 264 (5586) , 517-522
- https://doi.org/10.1038/264517a0
Abstract
Digestion of mouse liver nuclei with DNase II leads to a novel cleavage pattern with a 100-nucleotide pair periodicity. From chromatin, this pattern or the standard 200-nucleotide pair repeat can be produced depending on the ionic conditions. The results are interpreted by assuming different conformational states of the nuclear material, including condensed and extended forms.Keywords
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