Sensitivity analysis of a thin-film optical waveguide biochemical sensor using evanescent field absorption
- 1 July 1993
- journal article
- Published by Optica Publishing Group in Applied Optics
- Vol. 32 (19) , 3544-3549
- https://doi.org/10.1364/ao.32.003544
Abstract
A multichannel thin-film optical waveguide sensor for determining aqueous biochemical concentration with a high dynamic range of measurement is proposed. The sensitivity dependence of the proposed sensor on interaction length and waveguide thickness is investigated for dye solutions and three different hemoglobin concentration levels of carboxyhemoglobins. The sensitivity is inversely proportional to the waveguide thickness while proportional to the interaction length. As a consequence the variability of the interaction length makes the proposed sensor a flexible tool for concentration measurements. Moreover, an efficient method for determining the absorption coefficient is discussed.Keywords
This publication has 17 references indexed in Scilit:
- A Flow Cell for Mode-Specific, Integrated Optical Waveguide Spectroscopy in Aqueous SuperstratesApplied Spectroscopy, 1990
- Long path fiber-optic sensor for evanescent field absorbance measurementsAnalytical Chemistry, 1988
- Optical fibre sensors for chemical speciesJournal of Physics E: Scientific Instruments, 1988
- Long path length absorption measurements in thin dielectric filmsAnalytical Chemistry, 1987
- Fiber-optic evanescent field absorption sensorApplied Physics Letters, 1987
- Fiber-optic evanescent-wave methane-gas sensor using optical absorption for the 3392-μm line of a He–Ne laserOptics Letters, 1987
- Excitation of Fluorescent Emission from Solutions at the Surface of Polymer Thin-Film Waveguides: An Integrated Optics Technique for the Sensing of Fluorescence at the Polymer/Solution InterfaceApplied Spectroscopy, 1987
- Novel attenuated total internal reflectance spectroscopic cell using infrared fibers for aqueous solutionsApplied Physics Letters, 1986
- Liquid core optical fiber total reflection cell as a colorimetric detector for flow injection analysisAnalytical Chemistry, 1985
- A systematic investigation and characterization of interfacial hydrated n-alkane films by total internal multiple reflectionThe Journal of Chemical Physics, 1985