The estimation of the number of mutationally silent loci in saturation-mapping experiments
- 1 February 1980
- journal article
- research article
- Published by Hindawi Limited in Genetics Research
- Vol. 35 (1) , 33-44
- https://doi.org/10.1017/s0016672300013914
Abstract
SUMMARY: When the technique of saturation mapping is employed to estimate the number of loci in a distinct chromosomal region, there is always the possibility that some loci will not be detected. If the number of mutants per locus follows a Poisson distribution, the number of mutationally silent loci can be estimated. This paper describes a method for fitting such data to a Poisson distribution truncated at the zero class and a method for estimating the number of mutationally silent loci. The use of these methods is demonstrated by their application to some published data.This publication has 12 references indexed in Scilit:
- Fine gentic structure of the 2D3-2F5 region of the X-chromosome of Drosophila melanogasterMolecular Genetics and Genomics, 1975
- Cytogenetic and complementation analyses of recessive lethal mutations induced in theXchromosome ofDrosophilaby three alkylating agentsGenetics Research, 1974
- Analysis of a Whole Chromosome in DrosophilaCold Spring Harbor Symposia on Quantitative Biology, 1974
- Estimating the Parameter in a Conditional Poisson DistributionBiometrics, 1960
- The Significance of Deviations from Expectation in a Poisson SeriesPublished by JSTOR ,1950
- A REVISED MAP OF THE SALIVARY GLAND X-CHROMOSOME of Drosophila MelanogasterJournal of Heredity, 1938
- SALIVARY CHROMOSOME MAPSJournal of Heredity, 1935
- THE ACCURACY OF THE PLATING METHOD OF ESTIMATING THE DENSITY OF BACTERIAL POPULATIONSAnnals of Applied Biology, 1922