Effect of glycosaminoglycans on fibronectin‐mediated cell attachment
- 1 July 1982
- journal article
- research article
- Published by Wiley in Journal of Cellular Physiology
- Vol. 112 (1) , 5-9
- https://doi.org/10.1002/jcp.1041120103
Abstract
In this study, the role of glycosaminoglycans in fibronectin‐mediated cell attachment to collagen has been investigated. While it has been established that fibronectin possesses binding sites for several glycosaminoglycans, it was found that only dextran sulfate and macromolecular heparin could decrease the initial rate of cell attachment to collagen. Low molecular weight heparin was inactive. This study suggests that the glycosaminoglycan binding site of fibronectin plays a role in the mechanism of cell attachment.This publication has 39 references indexed in Scilit:
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