Biosynthese und Struktur des Fettsäuresynthetase-Komplexes der Hefe
- 1 July 1977
- journal article
- research article
- Published by Springer Nature in The Science of Nature
- Vol. 64 (7) , 366-370
- https://doi.org/10.1007/bf00368735
Abstract
Genetic as well as biochemical data suggest that the yeast fatty-acid synthetase complex has an (AB)6 protein structure where A and B represent multifunctional polypeptide chains with molecular weights of 185000 and 180000 daltons, respectively. Subunit A contains at least 3 and subunit B4 of the 8 known biochemical functions of the multienzyme complex. It is concluded that this complex structure has evolved from the corresponding prokaryotic system of monofunctional enzymes due to a selective advantage regarding the biosynthesis and assembly of the complex components.This publication has 53 references indexed in Scilit:
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