Glucose Transport by the Intestinal Mucosa of the Dogfish.

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Abstract
A simple technique using the mucosal membrane of dogfish gut to study the transport of glucose was presented. The mucosal membrane can transport glucose from the mucosal to the submucosal fluid against concentration gradients. This transport was greater at 36[degree] C than at 26[degree], and was inhibited by phlorizin, sodium azide, iodoacetic acid and uranyl acetate. Michaelis-Menten analysis of data has shown that inhibition of glucose transport by phlorizin was competitive at 26[degree]C and non-competitive at 36[degree]. It is postulated that a carrier system for glucose transport operates at the low temperature, while a more complicated mechanism handles glucose transport at 36[degree]C.

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