Retroviral Delivery of Noggin Inhibits the Formation of Heterotopic Ossification Induced by BMP-4, Demineralized Bone Matrix, and Trauma in an Animal Model
- 1 January 2004
- journal article
- Published by Wolters Kluwer Health in Journal of Bone and Joint Surgery
- Vol. 86 (1) , 80-91
- https://doi.org/10.2106/00004623-200401000-00013
Abstract
Background:The heterotopic ossification of muscles, tendons, and ligaments is a common problem faced by orthopaedic surgeons. We investigated the ability of Noggin (a BMP [bone morphogenetic protein] antagonist) to inhibit heterotopic ossification.Methods:Part 1: A retroviral vector carrying the genKeywords
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