Persistent Phenothiazine Dyskinesia Treated with Tetrabenazine

2 October 1971

journal article
clinical trial
Published by BMJ in BMJ

Vol. 4 (5778) , 25-26
https://doi.org/10.1136/bmj.4.5778.25

Abstract

Six patients with persistent phenothiazine dyskinesia were treated in a double-blind controlled trial with tetrabenazine 100 mg in divided dosage. In three patients the abnormal movements were abolished and in two others there was some improvement, but this was no greater than that achieved with the diazepam control. Tetrabenazine may be useful in the treatment of some patients with persistent phenothiazine dyskinesia.

Keywords

CONTROLLED TRIAL
FACIAL EXPRESSION

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CONCENTRATION OF HOMOVANILLIC ACID AND 5‐HYDROXYINDOLEACETIC ACID IN THE CEREBROSPINAL FLUID AFTER TREATMENT WITH PROBENECID IN PATIENTS WITH DRUG‐INDUCED TARDIVE DYSKINESIA
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