DEMONSTRATION OF A PITUITARY GONADOTROPHIN HORMONE ACTIVITY IN THE MALE FOETAL MOUSE
- 1 September 1976
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 83 (1) , 158-165
- https://doi.org/10.1530/acta.0.0830158
Abstract
Testosterone production by 18 day old fetal mouse testis was measured in an organ culture system by RIA [radioimmunoassay] of the culture medium. Production was time-dependent and could be stimulated by ovine LH [luteinizing hormone] and age-matched fetal pituitary. The gonadotropin activity derived from fetal pituitary appeared to be released into the culture medium as a limited reserve. A biologically active gonadotropin material appears in the pituitary of the 18 day old mouse fetus.This publication has 1 reference indexed in Scilit: