The formation of Hfr strains inEscherichia coliK12
- 1 February 1967
- journal article
- research article
- Published by Hindawi Limited in Genetics Research
- Vol. 9 (1) , 35-47
- https://doi.org/10.1017/s0016672300010296
Abstract
The isolation and characterization of an isogenic series of twelve Hfr strains is described. From their points of origin it was concluded that the sex factor integrates at a limited number of sites on the bacterial chromosome. Although the nutritional requirements of these Hfr strains were similar to those of the parent F+strain, it was observed that one group had a markedly slower growth rate. The relevance of these observations to theories on the nature of F+fertility and on the formation of Hfr strains is discussed.Keywords
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