Site-specific dehydrogenation of ring D in steroids

1 January 1970

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society D: Chemical Communications

No. 11,p. 659-661
https://doi.org/10.1039/c29700000659

Abstract

The 3α-cholestanyl ester of 5-(4-benzoylphenyl)-valeric acid underwent direct photochemical hydrogen transfer upon irradiation, thereby providing a simple route to Δ¹⁴ and Δ¹⁶ steroids, in 53% yield: a minor proportion of this reaction led to steroidal macrolides.

Keywords

DEHYDROGENATION
BENZOYLPHENYL
PHOTOCHEMICAL
MINOR
VALERIC
PROPORTION
MACROLIDES
CHOLESTANYL
Δ16
Δ14