Chronic Oral Toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) to Rainbow Trout
- 1 November 1977
- journal article
- research article
- Published by Oxford University Press (OUP) in Transactions of the American Fisheries Society
- Vol. 106 (6) , 641-645
- https://doi.org/10.1577/1548-8659(1977)106<641:cotott>2.0.co;2
Abstract
Rainbow trout (Salmo gairdneri) consumed diets containing 2.3 parts per trillion (10−12, pptr), 2.3 parts per billion (10−9, ppb), and 2.3 ppm TCDD 6 days each week for 105 days, resulting in an average intake of, respectively, 3.2 × 10−8, 3.6 × 10−5, or 2.1 × 10−2 μg/TCDD/g fish, freeze‐dry weight per day. Consumption of food containing 2.3 pptr or 2.3 ppb TCDD caused no mortality, no reduction in food consumption or growth, and no fin erosion. Consumption of diets containing 2.3 ppm TCDD caused an average mortality of 50% and 88% in 61 and 71 days, respectively. Feeding activity and growth were also reduced, and fin erosion and liver pathology increased. These data indicate that the “no‐effect” level for survival, growth, feeding activity, and fin erosion in rainbow trout receiving TCDD orally is between 2.3 ppm and 2.3 ppb.This publication has 0 references indexed in Scilit: