Growth Retardation and Corneal Vascularization with Tyrosine and Phenylalanine in a Purified Diet

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Abstract
The addition of 1% dl-phenyl-alanine and 1% [iota]( - )tyrosine to a purified diet containing 10% casein produced growth retardation and external lesions. Conversion of phenylalanine to tyrosine in the animal may add to the effect of the tyrosine. The addition of relatively large amts. of nicotinic acid or [iota](- )tryptophane appreciably alleviated the deleterious effects.