Abstract
Ovarian tissue from adult female rhesus macaques was transplanted into sc abdominal pouches of 4 male rhesus macaques that had been castrated after reaching sexual ovarian transplants. Two males in which the transplants were successful showed preovulatory-like gonadotropin surges in response to increasing levels of estradiol. In one of these males (7082), circulating levels of gonadotropins and steroids indicated that cyclic ovarian function had been established. This male showed 5 successive ovarian cycles that averaged 28 days in length. Comparison of the changes in reproductive hormones between 7082 and females with normal menstrual cycles support the hypothesis that the neuroendocrine mechanisms that regulate cyclic release of gonadotropins in primates are not sexually different.