ACUTE SEPTIC PEMPHIGUS

Abstract
The title "acute septic pemphigus" was selected because it describes a certain well defined entity better than plain "acute pemphigus," a term at times applied to chronic forms of malignant character with frequent remissions and severe manifestations. Acute septic pemphigus exhibits the same cutaneous appearance as chronic pemphigus, but differs in its rapid development, its early signs of systemic involvement and its rapid fatal termination. The whole picture is that of a fulminating septicemia attacking a system apparently without an immunizing protection. Acute septic pemphigus holds an ambiguous position in dermatology. Except for the assumption of an overwhelming bacteremia, the reason for the rapid development of the disease and death of the patients is obscure. Necropsies do not reveal sufficient evidence. Bacteriologic examinations have shown at different times the presence of Bacillus pyocyaneus, the streptococcus, the colon bacillus and other bacilli, but all of these, no doubt, play a secondary

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