Low frequency of MuSK antibody in generalized seronegative myasthenia gravis among Chinese

Abstract
During last 10 years, we collected data from 774 myasthenic patients (389 with the ocular type and 385 generalized type) at the Shin Kong Wu Ho-Su Memorial Hospital. Among patients with generalized MG, 38 (9.8%) were seronegative for AChRAb. We enrolled 26 of these patients, who had been monitored regularly; 20 were women and 6 were men (table). Twenty patients were in Osserman stage IIa, four were in IIb, and two patients were in stage III. Limb weakness was the most common …