Infection by Multiple Viruses and Lymphocyte Abnormalities at the Diagnosis of Diabetes

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Abstract
Evidence for an ongoing adenovirus infection and preceding EB and Coxsackie B virus infections was found in a 2‐year‐old boy at the diagnosis of insulin‐dependent diabetes. An inverted T‐helper/T‐suppressor lymphocyte ratio and activation of T cells with a suppressor‐cytotoxic phenotype were detected. A combination of multiple viral infections may be responsible for the rapid destruction of pancreatic beta cells in this case.