An efficient stereoselective method for the synthesis of thienamycin intermediates

1 January 1982

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications

No. 2,p. 104-105
https://doi.org/10.1039/c39820000104

Abstract

A three-step procedure for the synthesis of trans-3,4-disubstituted azetidin-2-ones which utilizes 1,3-dipolar cycloaddition as the key step has led to the synthesis of the azetidinones (16) and (17)

Keywords

EFFICIENT STEREOSELECTIVE
STEREOSELECTIVE METHOD
KEY STEP
DISUBSTITUTED AZETIDIN
THIENAMYCIN INTERMEDIATES
DIPOLAR CYCLOADDITION
STEP PROCEDURE