A Modified Procedure for the Determination of Isoniazid in Mixtures with Sodium p-Aminosalicylate
- 1 September 1962
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 14 (1) , 123-124
- https://doi.org/10.1111/j.2042-7158.1962.tb11064.x
Abstract
A modification of a routine method for the determination of isoniazid in mixtures with sodium p-aminosalicylate in tablet form is described. After the removal of interfering tablet excipients with hydrochloric acid the isoniazid is determined by reduction of the hydrazine group with a zinc-copper couple in potassium hydroxide to ammonia which is absorbed in standard acid the excess of which is titrated with standard alkali.Keywords
This publication has 1 reference indexed in Scilit:
- The Determination of Isoniazid in Pharmaceutical Preparations Containing Sodium p-AminosalicylateJournal of Pharmacy and Pharmacology, 1957