Facial Palsy in Hand-Schuller-Christian's Disease
- 1 November 1969
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA Otolaryngology–Head & Neck Surgery
- Vol. 90 (5) , 563-567
- https://doi.org/10.1001/archotol.1969.00770030565006
Abstract
HAND-Schüller-Christian's disease is a disseminated granulomatosis of unknown etiology. The clinical appearances are characterized by granulomas affecting mainly the skeletal system, especially the skull. The skin, the lymph node system, mucous membranes, and viscera may also be involved. The disease runs a typically chronic course with a tendency to remission. The histological appearance of the granulomas is fairly polymorphous. The cellular tissue is predominated, during the early stages, by reticulum cells, eosinophilic leukocytes, plasma cells, and polynuclear giant cells. At later stages there are foam cells containing cholesterol. The symptoms and signs are varied, but the otological signs occupy a preferential position, both by virtue of their common presence and their early appearance. Thus, many cases are seen first by the otologist (among the approximately 700 reported cases several have been published by otologists). I have1 collected 500 cases from the literature and reviewed the manifold ear, nose, andThis publication has 1 reference indexed in Scilit:
- Über die sogenannten primären LipoidosenEuropean Journal of Pediatrics, 1938