Exclusion of the gelsolin gene on 9q32-34 as the cause of familial lattice corneal dystrophy type I.

  • 1 July 1992
    • journal article
    • Vol. 51  (1) , 156-60
Abstract
Familial lattice corneal dystrophy type I (LCD1) is a localized form of inherited amyloidosis limited to the corneal stroma. Recently the Finnish form of hereditary amyloidosis with lattice corneal dystrophy has been shown to be due to a mutation in the gelsolin gene (G654----A; Asp187----Asn). In this paper we exclude the gelsolin gene as the cause of the autosomal dominant form of isolated LCD1.