Facial morphometry of Ecuadorian patients with growth hormone receptor deficiency/Laron syndrome.
Open Access
- 1 August 1994
- journal article
- research article
- Published by BMJ in Journal of Medical Genetics
- Vol. 31 (8) , 635-639
- https://doi.org/10.1136/jmg.31.8.635
Abstract
Facial morphometry using computerised image analysis was performed on patients with growth hormone receptor deficiency (Laron syndrome) from an inbred population of southern Ecuador. Morphometrics were compared for 49 patients, 70 unaffected relatives, and 14 unrelated persons. Patients with growth hormone receptor deficiency showed significant decreases in measures of vertical facial growth as compared to unaffected relatives and unrelated persons with short stature from other causes. This report validates and quantifies the clinical impression of foreshortened facies in growth hormone receptor deficiency.Keywords
This publication has 32 references indexed in Scilit:
- Mutation creating a new splice site in the growth hormone receptor genes of 37 Ecuadorean patients with Laron syndromeHuman Mutation, 1992
- Application of D'Arcy Thompson's coordinate transformation approach to clinical genetics photographs using image processing techniques.Journal of Medical Genetics, 1991
- Photogrammetric evaluation in clinical genetics: Theoretical considerations and experimental resultsAmerican Journal of Medical Genetics, 1991
- The Little Women of Loja — Growth Hormone–Receptor Deficiency in an Inbred Population of Southern EcuadorNew England Journal of Medicine, 1990
- Facial morphometrics in the identification of gene carriers of X-linked hypohidrotic ectodermal dysplasiaAmerican Journal of Medical Genetics, 1990
- The developing role of anthropologists in medical genetics: Anthropometric assessment of the Prader‐Labhart‐Willi syndrome as an illustrationMedical Anthropology, 1989
- Anthropometric evaluation of dysmorphology in craniofacial anomalies: Treacher Collins syndromeAmerican Journal of Physical Anthropology, 1987
- Describing a craniofacial anomaly: Finite elements and the biometrics of landmark locationsAmerican Journal of Physical Anthropology, 1987
- Facial effects of fetal alcohol exposure: Assessment by photographs and morphometric analysisAmerican Journal of Medical Genetics, 1987
- The geometry of craniofacial growth invariantsAmerican Journal of Orthodontics, 1983