SYNTHESIS OF γ‐CARBOXYGLUTAMIC ACID AND ITS DERIVATIVES VIA MANNICH‐BASE CONDENSATION
- 1 February 1980
- journal article
- research article
- Published by Wiley in International Journal of Peptide and Protein Research
- Vol. 15 (2) , 154-158
- https://doi.org/10.1111/j.1399-3011.1980.tb02562.x
Abstract
This report describes the synthesis of Nα-formyl and Nα-benzyloxycarbonyl-γγ-di-t-butyl-γ-carboxyglutamic acid via Mannich-base condensation starting from di-t-butyl malonate and diethyl formamido or benzyloxycarbonylamidomalonate.Keywords
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