Decrease in serum testosterone concentration during treatment with tetracycline

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Abstract
Serum concentrations of testosterone and the binding capacity of sex hormone binding globulin (SHBG) were measured on 2 days immediately preceding tetracycline treatment, on 3 days of treatment and on 2 days immediately after cessation of treatment. On the treatment days serum mean testosterone concentrations were significantly lower than on the control days (17 .+-. 0.9 vs. 21 .+-. 0.8 nmol/l, P < 0.01). There were no differences in the SHBG. The ''free testosterone index'' behaved like the total testosterone.

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