Abstract
Perioperative transfusion triggers for red blood cell (RBC) transfusion include physiologic signs of inadequate oxygenation of the entire organism or a specific organ. hemoglobin (Hb) concentration and logistic aspects such as experience of anesthesiologists and surgeons, predictability and magnitude of blood loss and time required for a Hb determination and RBC delivery. At a Hb concentration 50%, a a mixed‐venous O2 partial pressure 10% (not otherwise explained) and signs of locally deficient Oxygenation such as myocardial ischemia. At Hb concentrations >10 g/dL. RBC transfusions are rarely, if ever, indicated.