Changes in the Connective Tissue of Rats Fed Toxic Diets Containing Molybdenum Salts

Publisher Website
Google Scholar
Abstract
On a basal purified diet supplemented with 0.4 mMoles of sodium molybdate/100 g of diet for 35 days, the NMRI-D rat strain developed toxic characteristics. Of the animals fed this level of molybdenum 50% showed markedly poorer growth responses, low hemoglobin levels and low hematocrit values and developed macroscopic exostoses at the insertion site of the masseter muscle. Microscopically, the dental connective tissues showed morphologic changes closely resembling those of lathyrism.