Ringerʼs lactate with or without 3% dextran-60 as volume expanders during abdominal aortic surgery

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Abstract
To compare a solution of 3% dextran-60 (D60) in Ringer's lactate (RL) with RL alone as maintenance fluids for abdominal aortic surgery. Randomized control trial of 20 consecutive patients undergoing elective aortic reconstructive surgery. A surgical ICU in a university hospital. Consecutive patients, mean age 64 yr. Five patients had abdominal aneurysm, 12 had aortic obstruction disease, and three had aortic renal bypass surgery. These patients were followed for 1 month. Pulmonary artery occlusion pressure of at least 10 mm Hg and a urine output >30 mL/h were used to guide the intraoperative fluid infusion rates, which were 36 and 104 mL/kg of D60 and RL, respectively (ratio 1:2.9). Body weight at 24 hr had increased more with RL (7.8 kg) than with D60 (3.2 kg) infusion (p Conclusion A diluted colloid solution in Ringer's lactate is of significant value in maintaining intravascular volumes and hemodynamics during and after major operative procedures. (Crit Care Med 1991; 19:36)

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