Modelling ‘evo‐devo’ with RNA
- 22 November 2002
- Vol. 24 (12) , 1164-1177
- https://doi.org/10.1002/bies.10190
Abstract
The folding of RNA sequences into secondary structures is a simple yet biophysically grounded model of a genotype–phenotype map. Its computational and mathematical analysis has uncovered a surprisingly rich statistical structure characterized by shape space covering, neutral networks and plastogenetic congruence. I review these concepts and discuss their evolutionary implications. BioEssays 24:1164–1177, 2002. © 2002 Wiley‐Periodicals, Inc.Keywords
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