Intravenous Recombinant Tissue Plasminogen Activator in a Pregnant Woman With Cardioembolic Stroke
- 1 August 2006
- journal article
- review article
- Published by Wolters Kluwer Health in Stroke
- Vol. 37 (8) , 2168-2169
- https://doi.org/10.1161/01.str.0000230286.95513.c2
Abstract
Background and Purpose— Historically, the use of tissue plasminogen activator (tPA) thrombolysis in pregnancy has been regarded as relatively contraindicated. Underlying this stance has been the concern over the risk of bleeding complications in both mother and child. Summary of Case— We report the successful use of intravenous recombinant tPA (rtPA) thrombolysis in a pregnant woman with acute cardioembolic stroke. Conclusions— The patient improved clinically, did not develop complications after receiving rtPA, and at 37 weeks’ gestation, delivered a healthy infant, demonstrating that rtPA thrombolysis may be used safely in pregnant women.Keywords
This publication has 6 references indexed in Scilit:
- Thrombolytic Therapy for Acute Stroke in Late Pregnancy With Intra-Arterial Recombinant Tissue Plasminogen ActivatorStroke, 2005
- Stroke in pregnancyNeurologic Clinics, 2004
- Stroke in ovarian hyperstimulation syndrome in early pregnancy treated with intra-arterial rt-PANeurology, 2002
- Massive Pulmonary Embolism During Pregnancy Successfully Treated With Recombinant Tissue Plasminogen ActivatorArchives of internal medicine (1960), 2002
- Fibrinolysis with Alteplase in a Pregnant Woman with StrokeCerebrovascular Diseases, 2002
- Use of Thrombolytics for the Treatment of Thromboembolic Disease During PregnancyObstetrical & Gynecological Survey, 1995