Asymmetric Baylis–Hillman reactions: catalysis using a chiral pyrrolizidine base
- 1 January 1998
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 22,p. 2533-2534
- https://doi.org/10.1039/a806115g
Abstract
A novel chiral pyrrolizidine base 5 derived from L-proline promotes the Baylis–Hillman reaction of ethyl and methyl vinyl ketones with electron deficient aromatic aldehydes with moderate levels of enantiomeric excess.Keywords
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