Genesis of Respiratory and Circulatory Changes in Blast Injury

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Abstract
The changes in respiration and circulation caused by the exposure to a high explosive shock wave are entirely of peripheral origin without any cerebral concussion component. The instantaneous acceleration of respiration is due to vagal reflexes originating in the damaged lungs. The initiation of the bradycardia and blood pressure drop are concluded to be caused by the blast pressure acting directly upon the carotid sinus region whereas the more prolonged changes are due to reflexes evoked in the blast damaged lungs.

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