Porphyria Cutanea Tarda
- 1 June 1957
- journal article
- research article
- Published by American Medical Association (AMA) in A.M.A. Archives of Dermatology
- Vol. 75 (6) , 801-803
- https://doi.org/10.1001/archderm.1957.01550180015004
Abstract
Porphyria cutanea tarda, or chronic porphyria, is a rare disease, in which there is vesicle formation on parts exposed to the sun, especially the face and hands. Its successful treatment has not previously been reported, even with the use of the steroid hormones, dimercaprol (BAL),1folic acid, vitamin B12, or riboflavin.2 Chloroquine has been used more or less successfully in the treatment of chronic discoid lupus erythematosus,3solar dermatitis, and hydroa estivale,4all considered to be related to sunlight sensitivity. Because of the definite relationship of bulla and vesicle formation, following exposure to the sun, in a patient with chronic porphyria, chloroquine has been tried and found to clear the lesions completely in a short time. The case report of this patient follows: A 47-year-old white man came in on Feb. 2, 1955, with a history of an eczematoid blistering eruption onKeywords
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