Differential Association of CD45 Isoforms with CD4 and CD8 Regulates the Actions of Specific Pools of p56lck Tyrosine Kinase in T Cell Antigen Receptor Signal Transduction
Open Access
- 1 January 2002
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 277 (3) , 1912-1918
- https://doi.org/10.1074/jbc.m108386200
Abstract
No abstract availableKeywords
This publication has 46 references indexed in Scilit:
- The Adapter Type Protein CMS/CD2AP Binds to the Proto-oncogenic Protein c-Cbl through a Tyrosine Phosphorylation-regulated Src Homology 3 Domain InteractionPublished by Elsevier ,2001
- The CD45 tyrosine phosphatase: a positive and negative regulator of immune cell functionSeminars in Immunology, 2000
- CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation.The Journal of Experimental Medicine, 1996
- Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes.The Journal of Experimental Medicine, 1996
- The extracellular domain of CD45 controls association with the CD4-T cell receptor complex and the response to antigen-specific stimulation.The Journal of Experimental Medicine, 1996
- Distinct Isoforms of the CD45 Protein-tyrosine Phosphatase Differentially Regulate Interleukin 2 Secretion and Activation Signal Pathways Involving Vav in T CellsJournal of Biological Chemistry, 1995
- Isoforms of the transmembrane tyrosine phosphatase cd45 differentially affect T cell recognitionImmunity, 1994
- Normal B lymphocyte development but impaired T cell maturation in CD45-Exon6 protein tyrosine phosphatase-deficient miceCell, 1993
- Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathwayNature, 1990
- Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens.The Journal of Experimental Medicine, 1987