Correlative clinico‐pathological evaluation of oral premalignancy

Abstract
In 1972, the WHO''s, Meeting of Investigators on the Histological Definitions in Precancerous Lesions defined a precancerous lesion as a morphologically altered tissue in which cancer is more likely to occur than in its apparently normal counter part. There are 2 generally accepted precancerous lesions in the [human] oral cavity,leukoplakia and erythroplakia. Leukoplakia is currently defined as a white patch or plaque that cannot be characterized clinically or pathologically as any other disease (WHO 1978). This definition has no histological connotation and is used in a strictly clinical sense. Erythroplakia is defined as a bright red velvety plaque which cannot be characterized clinically or pathologically as being due to any other condition.