Homologous gene knockout in the archaeon Halobacterium salinarum with ura3 as a counterselectable marker
- 1 February 2000
- journal article
- research article
- Published by Wiley in Molecular Microbiology
- Vol. 35 (3) , 667-676
- https://doi.org/10.1046/j.1365-2958.2000.01739.x
Abstract
To facilitate the functional genomic analysis of an archaeon, we have developed a homologous gene replacement strategy for Halobacterium salinarum based on ura3, which encodes the pyrimidine biosynth...Keywords
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