POSTOPERATIVE PAIN AND ANXIETY: A Comparison of Pentazocine alone and Pentazocine combined with Oxypertine in Postoperative Pain and Anxiety

Open Access
Publisher Website
Google Scholar
Abstract
The relief of postoperative pain and anxiety by pentazocine alone, and pentazocine combined with oxypertine (a phenyl-piperazine anxiolytic) is compared in 234 randomized patients. With the pentazocine-oxypertine combination significantly less patients needed further analgesics. There was no significant difference in the few side effects in both groups. There was greater relief of both pain and anxiety in most groups who received the pentazocine-oxypertine combination. The mean pain relief score at 2 hours for observer and patients combined was 1.05 for the pentazocine group and 1.16 for the pentazocine-oxypertine group. The mean anxiety relief score at 4 hours for both patient and observer was 0.275 in the pentazocine group compared with 0.335 in the pentazocine-oxypertine group. However, these changes showed only a trend and were not statistically significant. This combination should prove safe and useful when a postoperative patient is suffering from both pain and anxiety.

This publication has 0 references indexed in Scilit: