Pulmonary Function and Oxygen Uptake During Exercise in 16 Year Old Boys with Cystic Fibrosis

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Abstract
Eight of 9 Norwegian boys with cystic fibrosis (CF), aged 15-17 yr, and 8 healthy boys of the same age underwent pulmonary function and bicycle exercise testing. Although the CF boys showed large individual variations, the 2 groups showed great differences in mean body height and weight, pulmonary function variables and maximum O2 uptake. The maximum O2 uptake for the CF boys ranged from 40 to 125% (mean 79%) of predicted values. Increased ventilatory equivalent for O2 was a characteristic finding during rest and exercise for the CF boys, and their O2 uptake was higher during rest and corresponding work loads compared with the controls. As physical training is beneficial in CF, such exercise tests are of value for prescribing individual training programs and in evaluating their effects.

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