Extraction and High Performance Liquid Chromatographic Determination of Enrofloxacin in Fish Serum and Tissues
- 1 February 1991
- journal article
- research article
- Published by Taylor & Francis in Journal of Liquid Chromatography
- Vol. 14 (3) , 521-531
- https://doi.org/10.1080/01483919108049267
Abstract
The extraction of enrofloxacin from fish serum and tissues using solid phase extraction columns has been studied. Good recoveries were obtained by using C2 columns for cleanup of serum and C18 columns for clean-up of tissue samples. the sample pretreatment procedures are selective and robust having a sensitivity of 1 ng/ml and 1 ng/g from serum and tissues, respectively, making them particularly useful for monitoring drug residue levels. the recoveries were 97–100% from serum and 96–99% from tissues. the method was tested on fish treated with enrofloxacin.Keywords
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