PHAGOCYTIC PROPERTIES DISPLAYED BY MOUSE HEPATOCYTES AFTER VIRUS-INDUCED DAMAGE OF SINUSOIDAL LINING
- 1 January 1978
- journal article
- research article
- Vol. 29 (1) , 25-28
Abstract
Frog virus 3 (FV 3) inoculated i.v. into mice damages sinusoidal cells and produces a decrease in the C uptake capacity of the liver. Histological and ultrastructural examinations showed that in FV 3 infected animals part of the inoculated C is taken up by the hepatocytes and can be located inside cytoplasmic vesicles or dense bodies. The hepatocytes are also able to phagocyte latex particles of 312 nm in diameter. Once the Kupffer cells and the endothelial lining are damaged, hepatocytes can display phagocytic properties.This publication has 3 references indexed in Scilit:
- Hepatocellular necrosis during frog virus 3-induced hepatitis of mice: An electron microscopic studyExperimental and Molecular Pathology, 1977
- Induction of pinocytosis in rat hepatocytes by partial hepatectomy.The Journal of cell biology, 1977
- LYSOSOMAL DEGRADATION OF CELL ORGANELLES .3. UPTAKE AND DISAPPEARANCE IN KUPFFER CELLS OF INTRAVENOUSLY INJECTED ISOTOPE-LABELED MITOCHONDRIA AND MICROSOMES INVIVO AND INVITRO1975